SCHOOL OF MEDICINE - DEPARTMENT OF BASIC SCIENCES
Mario Felipe
NEGRETTE GUZMÁN
Director of FARMET
Research Group
CONTACT
Information
maneguz@uis.edu.co
+57 (607) 634 4000
Extension: 3559
GENERAL
Biography
Professor Mario Negrette directs and actively participates in undergraduate courses at the School of Health, the Master’s program in Basic Biomedical Sciences, and the Ph.D. program in Biomedical Sciences. In addition, he oversees the training of master’s and doctoral students. One of his primary research focuses is enhancing the effectiveness and safety of chemotherapy for patients through the utilization of combination strategies involving bioactive molecules. These strategies aim to achieve a higher therapeutic index. This research entails the investigation of reprogramming mechanisms related to metabolism and cellular redox homeostasis, which sensitize the treatment target and/or protect other tissues from adverse toxic effects.
EDUCATION AND
Qualifications
-
PhD in Biochemical Sciences
Universidad Nacional Autónoma de México UNAM, 2016
-
Master in Biochemical Sciences
Universidad Nacional Autónoma de México UNAM, 2012
-
Chemist
Universidad de Córdoba, 2004
Director of FARMET
Research Group
CONTACT
Information
maneguz@uis.edu.co
+57 (607) 634 4000
Extension: 3559
AREAS OF
Expertise
- Biochemistry and redox regulation
- Energy metabolism
- Cancer cell biology
- Pharmacology
- Cell culture
- Animal experimental models
OFFICE
Hours
Tuesday to Friday
10:00 a.m. – 12:00 m.
Sede UIS Guatiguará, Edificio de Investigaciones EDI, Laboratorio 208 Farmacalogía y Metabolismo FARMET
Outstanding
Works
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Sulforaphane induces differential modulation of mitochondrial biogenesis and dynamics in normal cells and tumor cells
Article, Food Chem Toxicol, 2017
-
Curcumin attenuates gentamicin-induced kidney mitochondrial alterations: possible role of a mitochondrial biogenesis mechanism
Article, Evid Based Complement Alternat Med, 2015
AWARDS AND
Recognitions
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Mention Meritorious Thesis
Universidad de Córdoba, 2004
-
Beneficiary of the Francisco José de Caldas Scholarship Program
Convocatoria 497 de 2009, COLCIENCIAS, 2009
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Fellow of the National Council of Science and Technology
CONACYT, 2012